Marken’s 24/7 Cell & Gene Control Tower Provides Agile Solution for Critical Shipments

Marken’s Cell and Gene Control Tower re-routed six critical shipments of CAR-T drug products from Amsterdam to the UK and Spain, overcoming scheduling conflicts and logistical obstacles caused by the airline carrier and regional regulatory hurdles. The shipments arrived ahead of time and within specifications, valued at an estimated $380K, allowing non-Hodgkin’s lymphoma patients to receive their commercial CAR-T drug product.

Navigating multiple supply chain challenges to safeguard delivery of urgent commercial CAR-T cell drug product to UK and Spain



Successfully re-route six critical shipments to the UK and Spain from Amsterdam to deliver CAR-T drug products used to treat non-Hodgkin’s lymphoma cancer patients.


  • Scheduling conflicts and logistical obstacles caused by airline carrier of origin
  • Overcome limited staff and resources over the weekend
  • Navigate regional regulatory hurdles associated with an EU shipment entering anon-EU nation (UK)
  • Meeting critical time and temperature requirements to ensure stability of the CAR-T cell drug product


Marken’s Cell and Gene Control Tower efficiently detected the incorrect shipment offload in Amsterdam. Our Cell and Gene Therapy (CGT) London Operations team worked closely with the client to quickly determine regulatory requirements, contingency plans and backup route strategies. Throughout the weekend hours, our team coordinated the shipments to be picked up by a Desk-to-Desk Courier (DTDC) and ensured customs clearance and final mile delivery.


Shipments arrived ahead of time and within specifications, valued at an estimated $380K.With Marken’s proactive continuity planning, flexible solutions and specialized CGT team, patients being treated for non-Hodgkin’s lymphoma successfully received their commercial CAR-T drug product.


Marken is a wholly owned subsidiary of UPS and is a critical part of UPS Healthcare. With Polar Speed and Marken included, the UPS Healthcare division staffs 128 locations with 5,500 employees worldwide. Marken offers a state-of-the-art GMP-compliant depot network and logistic hubs for clinical drug product storage and distribution in 58 locations worldwide, while maintaining the leading position for Direct-to-Patient and Home Healthcare services, biological sample shipments and biological kit production. Marken’s dedicated 2,400+ staff members manage 154,000 drug product and biological sample shipments every month at all temperature ranges in more than 220 countries and territories and have orchestrated 14,000+ home healthcare visits. Additional services such as cell and gene supply chain services, ancillary material sourcing, storage and distribution, shipment lane verification and qualifications, as well as GDP, regulatory and compliance consultancy add to Marken’s unique position in the pharma and logistics industry.

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